Left Cardiac Sympathetic Denervation [LCSD]

A surgical antiadrenergic intervention with a strong antiarrhythmic effect, supported by preclinical as well as clinical data. The mechanism of action of LCSD in structurally normal hearts with increased arrhythmic susceptibility (such as those of patients with channelopathies) is not limited to the antagonism of acute catecholamines release in the heart. denervation of the left cardiac sympathetic nerves has been successfully used to decrease the frequency of potentially lethal ventricular arrhythmias in Long QT syndrome